Industrial
Applications of Biotechnology
Dr.
Teresita M. Espino
Director, National Instutute of Molecual Biology and Biotechnology,
UP Los Baños
ABSTRACT
The applications
of the tools of biotechnology in the industry sector can be categorized
as:
- Microbial
based- technologies
-
Production
of biochemicals and pharmaceuticals (read article
on BIO-N, a biofertilizer made with Azospirillum
bacterium)
-
Bioconversion
of local raw materials into high value prodcuts through
enzyme-catalyzed reactions
- Rapid detection/screening
of pathogens and toxins
Design of bioreactors
and biosensors
Traditional
fermented foods, organic acids, alcohols, amino acids, vitamins,
antibiotics; food- and feed additives produced by microbial action
have been subjects of extensive research in the Philippines. Bioconversion
of agro-industrial wastes or by-products into high value-products
through the action of enzymes have likewise been explored. Better
breeds of plants, fish and livestock have enriched the agriculture
and agro-industrial sectors. The abundant natural resources, including
a rich microbial germplasm diversity have sustained our R&D
efforts. Presently, intervention from modern biotechnology promises
achievment in faster growth and porduction rates, reduced downtime
in processing and lesser use of polluting chemicals.
Enzyme engineering
is a pioneering field in the Philippines. The bulk of enzyme requirement
for medical-, industrial areas, as well as those for basic research
is imported. fast tracking research on enzymes can provide solutions
to this need. Local production of enzymes ensures not only ready
availability of the commodity buyt will also avoid lost time from
shipment delay, loss of enzyme activity and conserve much-needed
dollars. Furthermore, enzyme-catalyzed bioconversion reactions are
preferred over chemical methods because of the lower operating temperatures,
less amount of undesirable by-products or racemic forms and less
amount of polluting extraction solvents.
Rapid indexing
of planting materials and livestock enables early control measures
to be applied to prevent outbreak of diseases. The importance of
early detection either by antibody or DNA based methods has been
underscored, particularly in the recent Mad Cow and Foot and Mouth
Disease scare in Europe. Detection of genetically modified organisms
as contaminants in transboundary shipment of grains and farm produce
has likewise triggered legislative action and reexamination of global
trade.
Food and feed
borne pathogens, mycotoxins in stored grains, toxins (microbial
or otherwise) in fishing grounds remain serious problems requiring
prompt and proactive detection and control strategies.
Industries must
also cope with the wastes that they generate. cleaner or "greener"
production technologies are being introduced or refined in our emerging
borderless world. shipment of toxic wastes across national boundaries
is becoming a contentious issue. where appropriate, bioreactors
are being designed, process controls streamlined, biosensors employed
to monitor critical production parameters and even the flow of recalcitrant
pollutants in the environment.
The industry
sector still has much to gain from biotechnology. Research and development
efforts must be adequately suported to give more and better globally
competitive products and services. The benefits of biotechnology
in terms of heftier return-on-investments for the industrialist,
more and better options for the consumer and a greener environment
are too important to be denied.
Parallel
session speakers:
| "Postharvest
Technology" |
Dr.
Concepcion C. Lizada
Bureau of Agriculture and Fisheries Porduct Standards
Department of Horticulture, UPLB |
| "Heavy
Metal Removal by a Novel Chelating Flocculant System" |
Dr.
Ronald Navarro
Department of Chemical Engineering, UPLB
|
| "Opportunities
and Constraints in Biotechnological R&D for the Food Industry" |
Dr.
Priscilla C. Sanchez
Department of Food Science and Technology, UPLB |
| "Local
Vaccine Industry: Present Constraints and Strategies for Future
Development" |
Dr. Phan
Quang Vinh
Biologics Corporation/
UPLB Science and Technology Park |
|